Japan is set to bolster its infectious disease research capabilities with a new biosafety level-4 (BSL-4) laboratory at Nagasaki University. Designed to handle highly lethal pathogens like the Ebola virus, the facility aims to strengthen the country’s response to emerging health threats. However, the project has raised concerns over potential safety risks.
Why Japan Needs a BSL-4 Lab
With climate change and environmental degradation accelerating the spread of infectious diseases, the world faces a growing risk of new pandemics. As global travel and trade intensify, so does the likelihood of a virus crossing borders at an alarming pace.

Japan’s lack of domestic BSL-4 facilities became evident during the COVID-19 pandemic, when the country had to rely heavily on foreign laboratories for research and vaccine development. To reduce this dependence, the government is pushing for more advanced research infrastructure.
Existing vs. New Lab: What’s the Difference?
Japan currently operates a single BSL-4 facility at the National Institute of Infectious Diseases (NIID) Murayama branch in Tokyo. However, due to public pressure, the government is considering relocating it outside the city.
Unlike the NIID facility, which primarily focuses on diagnostics, the new Nagasaki University lab will conduct in-depth research, including vaccine development and treatment innovations. This expansion marks a major step in Japan’s ability to combat emerging infectious diseases.
Public Concerns: A Disaster Waiting to Happen?
Despite its scientific importance, the project faces strong opposition. Some residents near the proposed site worry about accidental pathogen leaks, with online discussions even comparing the risks to a nuclear disaster.
To address these fears, strict safety measures will be in place:
- Complete air isolation to prevent leaks
- Advanced containment protocols
- Researchers wearing full-body protective suits
Global Context: Japan Joins the Club
Currently, over 60 BSL-4 labs exist worldwide across more than 20 countries. These high-security facilities are essential for rapid disease response, as relying on foreign labs in emergencies is not always feasible. Many are located within universities and research institutes in urban areas, similar to Japan’s plan for Nagasaki University.
With infectious diseases posing an ever-growing threat, Japan’s investment in its own high-level research infrastructure is not just a precaution—it’s a necessity. However, balancing scientific progress with public safety concerns will be the real challenge.